I checked MCC and avrdude is:

- avrdude.png (7.13 KiB) Viewed 3951 times
lsusb is giving this result:
$ lsusb
Bus 002 Device 005: ID 1781:0c9f Multiple Vendors USBtiny
Bus 002 Device 004: ID 046d:0825 Logitech, Inc. Webcam C270
Bus 002 Device 003: ID 17ef:1008 Lenovo Hub
Bus 002 Device 002: ID 8087:0020 Intel Corp. Integrated Rate Matching Hub
Bus 002 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub
Bus 004 Device 002: ID 0bc2:50a5 Seagate RSS LLC FreeAgent GoFlex Desk USB 3.0
Bus 004 Device 001: ID 1d6b:0003 Linux Foundation 3.0 root hub
Bus 003 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub
Bus 001 Device 006: ID 17ef:4816 Lenovo Integrated Webcam
Bus 001 Device 008: ID 046d:c52b Logitech, Inc. Unifying Receiver
Bus 001 Device 007: ID 413c:2005 Dell Computer Corp. RT7D50 Keyboard
Bus 001 Device 005: ID 17ef:1007 Lenovo
Bus 001 Device 004: ID 0a5c:217f Broadcom Corp. BCM2045B (BDC-2.1)
Bus 001 Device 003: ID 147e:2016 Upek Biometric Touchchip/Touchstrip Fingerprint Sensor
Bus 001 Device 002: ID 8087:0020 Intel Corp. Integrated Rate Matching Hub
Bus 001 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub
$
and I can see the tinyUSB on the first row.
When I started my laptop this morning avrdude find the USB-device and I could upload the program.
Mybee the problem have to do with the laptop. Because I some times can have the Arduino IDE to work correctly.
Now I know where to look when I get in trouble.
Thanks for help!